The Singapore-MIT Alliance for Research and Technology (SMART) is a leading research centre in Asia established by the Massachusetts Institute of Technology (MIT) and the National Research Foundation (NRF) of Singapore to identify and conduct research on critical problems of societal significance for today and the future.

Exemplifying the MIT spirit of research excellence and Singapore’s commitment to R&D, SMART advances high-impact research within and beyond CREATE, building strategic partnerships with universities, research institutes, hospitals, government agencies and industry.

SMART fosters a creative and collaborative environment that stimulates major discoveries through its interdisciplinary structure. Its five Interdisciplinary Research Groups (IRGs) are as follows:

  • Antimicrobial Resistance (AMR)
    • AMR leverages the scientific and clinical strengths of MIT and Singapore to develop transformative technologies to identify, respond to, and treat drug-resistant microbes.
  • Disruptive and Sustainable Technologies for Agricultural Precision (DISTAP)
    • Aims to revolutionalize how food is produced to meet the demands of a growing population in an increasing resource constrained world.
  • Future Urban Mobility (FM)
    • Developing a new paradigm for the planning, design, and operation of future urban passenger and freight transportation systems that enhance sustainability and societal well-being
  • Infectious Diseases (ID)
    • Investigating infectious diseases with a focus on influenza, tuberculosis, malaria and dengue


  • Low Energy Electronic Systems (LEES)
    • Developing new integrated circuits with reduced energy per function for applications in wireless communication, power electronics, LED lighting, printing, displays and computing

SMART also consists of the SMART Innovation Centre - the translational research arm of SMART - which is modelled after MIT’s Deshpande Center. It uses Adaptive Innovation to assist researchers from Singapore to pursue novel avenues of market-driven research and helps accelerate their innovations toward commercialisation.

SMART at a glance

  • First CREATE entity, established in 2007
  • First, and to-date largest, MIT research centre outside the US
  • Engages about 800 MIT & Singapore researchers
  • In the NEWS for its breakthroughs and discoveries
  • Collaborates with universities, research institutes, hospitals, government agencies and industry
  • Offers opportunity to work with MIT faculty, researchers and students
  • Offers Innovation Grants to inspire commercialisation 

Download the SMART AMR 
IRG Factsheet

SMART AMR front of factsheet 

Download the SMART BioSyM 
IRG Factsheet

SMART BioSyM front

Download the SMART CENSAM 
IRG Factsheet


Download the SMART DISTAP
IRG Factsheet

SMART DISTAP  front of factsheet


Download the SMART FM 
IRG Factsheet

FM2 Front   

Download the SMART ID 
IRG Factsheet

SMART ID factsheet front

Download the SMART LEES
IRG Factsheet


Download the SMART Innovation
Centre Factsheet


Contact Us
General Line: +65 6516 8603

Where to Find Us
Singapore 138602

Search for "Singapore MIT Alliance"

Download the SMART CENSAM 
IRG Factsheet